A Phosphoinositide 3-Kinase (PI3K)-serum- and glucocorticoid-inducible Kinase 1 (SGK1) Pathway Promotes Kv7.1 Channel Surface Expression by Inhibiting Nedd4-2 Protein

Epithelial cell polarization involves several kinase signaling cascades that eventually divide the surface membrane into an apical and a basolateral part. One kinase, which is activated during the polarization process, is phosphoinositide 3-kinase (PI3K). In MDCK cells, the basolateral potassium cha...

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Detalhes bibliográficos
Main Authors: Andersen, Martin Nybo, Krzystanek, Katarzyna, Petersen, Frederic, Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, Hugues, Jespersen, Thomas, Rasmussen, Hanne Borger
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873543/
https://ncbi.nlm.nih.gov/pubmed/24214981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525931
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