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Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus

In the mouse hypothalamus, ciliary neurotrophic factor (CNTF) is mainly expressed by ependymal cells and tanycytes of the ependymal layer covering the third ventricle. Since exogenously administered CNTF causes reduced food intake and weight loss, we tested whether endogenous CNTF might be involved...

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Hlavní autoři: Severi, Ilenia, Perugini, Jessica, Mondini, Eleonora, Smorlesi, Arianna, Frontini, Andrea, Cinti, Saverio, Giordano, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873503/
https://ncbi.nlm.nih.gov/pubmed/24409114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2013.00263
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