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Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia
Acute myeloid leukemia subtype M4 with eosinophilia is associated with a chromosome 16 inversion that creates a fusion gene CBFB-MYH11. We have previously shown that CBFB-MYH11 is necessary but not sufficient for leukemogenesis. Here, we report the identification of genes that specifically cooperate...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15044690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400930101 |
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