Phosphorylation of AKT and Abdominal Aortic Aneurysm Formation

It is hypothesized that differential AKT phosphorylation between sexes is important in abdominal aortic aneurysm (AAA) formation. Male C57BL/6 mice undergoing elastase treatment showed a typical AAA phenotype (80% over baseline, P < 0.001) and significantly increased phosphorylated AKT-308 (p308)...

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Main Authors: Ghosh, Abhijit, Lu, Guanyi, Su, Gang, McEvoy, Brendan, Sadiq, Omar, DiMusto, Paul D., Laser, Adriana, Futchko, John S., Henke, Peter K., Eliason, Jonathan L., Upchurch, Gilbert R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873487/
https://ncbi.nlm.nih.gov/pubmed/24332015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.016
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