Increased PAI-1 in females compared with males is protective for abdominal aortic aneurysm formation in a rodent model

The serine proteases, along with their inhibitor plasmin activator inhibitor-1 (PAI-1), have been shown to play a role in abdominal aortic aneurysm (AAA) formation. The aim of this study is to determine if PAI-1 may be a protective factor for AAA formation and partially responsible for the gender di...

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Auteurs principaux: DiMusto, Paul D., Lu, Guanyi, Ghosh, Abhijit, Roelofs, Karen J., Su, Gang, Zhao, Yunge, Lau, Christine L., Sadiq, Omar, McEvoy, Brendan, Laser, Adriana, Diaz, Jose A., Wakefield, Thomas W., Henke, Peter K., Eliason, Jonathan L., Upchurch, Gilbert R.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Vascular Biology and Microcirculation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330791/
https://ncbi.nlm.nih.gov/pubmed/22307671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00620.2011
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