Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-Conditioned uPA-NOG Mice

Human-specific HIV-1 and hepatitis co-infections significantly affect patient management and call for new therapeutic options. Small xenotransplantation models with human hepatocytes and hematolymphoid tissue should facilitate antiviral/antiretroviral drug trials. However, experience with mouse stra...

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Hlavní autoři: Gutti, Tanuja L., Knibbe, Jaclyn S., Makarov, Edward, Zhang, Jinjin, Yannam, Govardhana R., Gorantla, Santhi, Sun, Yimin, Mercer, David F., Suemizu, Hiroshi, Wisecarver, James L., Osna, Natalia A., Bronich, Tatiana K., Poluektova, Larisa Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2014
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873481/
https://ncbi.nlm.nih.gov/pubmed/24200850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.008
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