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Tandem Repeat Modification during Double-Strand Break Repair Induced by an Engineered TAL Effector Nuclease in Zebrafish Genome

Tandem repeats (TRs) are abundant and widely distributed in eukaryotic genomes. TRs are thought to have various functions in gene transcription, DNA methylation, nucleosome position and chromatin organization. Variation of repeat units in the genome is observed in association with a number of diseas...

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Detalhes bibliográficos
Main Authors: Huang, Wanxu, Zheng, Jianbo, He, Ying, Luo, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873399/
https://ncbi.nlm.nih.gov/pubmed/24386347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084176
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