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Tandem Repeat Modification during Double-Strand Break Repair Induced by an Engineered TAL Effector Nuclease in Zebrafish Genome

Tandem repeats (TRs) are abundant and widely distributed in eukaryotic genomes. TRs are thought to have various functions in gene transcription, DNA methylation, nucleosome position and chromatin organization. Variation of repeat units in the genome is observed in association with a number of diseas...

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Main Authors: Huang, Wanxu, Zheng, Jianbo, He, Ying, Luo, Chen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873399/
https://ncbi.nlm.nih.gov/pubmed/24386347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084176
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