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QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

The signaling activities of multiple developmental ligands require sulfated heparan sulfate (HS) proteoglycans as coreceptors. QSulf1 and its mammalian orthologs are cell surface HS 6-O-endosulfatases that are expressed in embryonic mesodermal and neural progenitors and promote Wnt signal transducti...

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Hlavní autoři: Wang, Shouwen, Ai, Xingbin, Freeman, Stephen D., Pownall, Mary E., Lu, Qun, Kessler, Daniel S., Emerson, Charles P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC387334/
https://ncbi.nlm.nih.gov/pubmed/15051888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401028101
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