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Gucosamine-6-sulfamate Analogs of Heparan Sulfate as Inhibitors of Endosulfatases
[Image: see text] Keeping Sulfate. The extracellular endosulfatases, which modulate signalling pathways by removing sulfate groups from heparan, can be inhibited by replacing the 6-sulfate destined for cleavage with an inhibitory sulfamate motif, as demonstrated by simple glucosamine-6-sulfamate ana...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086843/ https://ncbi.nlm.nih.gov/pubmed/20973023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000401 |
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