TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity

BACKGROUND: Patients with diabesity have a significantly increased risk of developing cardiovascular disease. Therefore, therapy addressing the multiple metabolic abnormalities linked with diabesity and leading to further reduction of cardiovascular risk is highly desirable. Activation of the TGR5 r...

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Bibliographic Details
Main Authors: Zambad, Shitalkumar P, Tuli, Davinder, Mathur, Anoop, Ghalsasi, Sameer A, Chaudhary, Anita R, Deshpande, Shailesh, Gupta, Ramesh C, Chauthaiwale, Vijay, Dutt, Chaitanya
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873233/
https://ncbi.nlm.nih.gov/pubmed/24379686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S50209
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