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TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity

BACKGROUND: Patients with diabesity have a significantly increased risk of developing cardiovascular disease. Therefore, therapy addressing the multiple metabolic abnormalities linked with diabesity and leading to further reduction of cardiovascular risk is highly desirable. Activation of the TGR5 r...

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Detalhes bibliográficos
Main Authors: Zambad, Shitalkumar P, Tuli, Davinder, Mathur, Anoop, Ghalsasi, Sameer A, Chaudhary, Anita R, Deshpande, Shailesh, Gupta, Ramesh C, Chauthaiwale, Vijay, Dutt, Chaitanya
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873233/
https://ncbi.nlm.nih.gov/pubmed/24379686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S50209
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