The PAF Complex and Prf1/Rtf1 Delineate Distinct Cdk9-Dependent Pathways Regulating Transcription Elongation in Fission Yeast

Cyclin-dependent kinase 9 (Cdk9) promotes elongation by RNA polymerase II (RNAPII), mRNA processing, and co-transcriptional histone modification. Cdk9 phosphorylates multiple targets, including the conserved RNAPII elongation factor Spt5 and RNAPII itself, but how these different modifications media...

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Main Authors: Mbogning, Jean, Nagy, Stephen, Pagé, Viviane, Schwer, Beate, Shuman, Stewart, Fisher, Robert P., Tanny, Jason C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873232/
https://ncbi.nlm.nih.gov/pubmed/24385927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004029
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