A Positive Feedback Loop Links Opposing Functions of P-TEFb/Cdk9 and Histone H2B Ubiquitylation to Regulate Transcript Elongation in Fission Yeast

Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification. Whereas histone modifications have established roles in transcription initiation, their functions during elongation are not understood. Mono-ubiquitylation of histone H2B (H2Bub1) plays...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sansó, Miriam, Lee, Karen M., Viladevall, Laia, Jacques, Pierre-Étienne, Pagé, Viviane, Nagy, Stephen, Racine, Ariane, St. Amour, Courtney V., Zhang, Chao, Shokat, Kevan M., Schwer, Beate, Robert, François, Fisher, Robert P., Tanny, Jason C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410854/
https://ncbi.nlm.nih.gov/pubmed/22876190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002822
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