Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin

The tumor suppressor protein p53 is known to induce either apoptosis or growth arrest depending on cellular background. We have previously reported that a bacterial redox protein azurin induces apoptosis in J774 cell line-derived macrophages whereas a site-directed mutant M44KM64E azurin shows very...

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Bibliographic Details
Main Authors: Yamada, Tohru, Hiraoka, Yoshinori, Ikehata, Masateru, Kimbara, Kazuhide, Avner, Benjamin S., Das Gupta, Tapas K., Chakrabarty, Ananda M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387323/
https://ncbi.nlm.nih.gov/pubmed/15044691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400899101
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