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Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin

The tumor suppressor protein p53 is known to induce either apoptosis or growth arrest depending on cellular background. We have previously reported that a bacterial redox protein azurin induces apoptosis in J774 cell line-derived macrophages whereas a site-directed mutant M44KM64E azurin shows very...

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Détails bibliographiques
Auteurs principaux: Yamada, Tohru, Hiraoka, Yoshinori, Ikehata, Masateru, Kimbara, Kazuhide, Avner, Benjamin S., Das Gupta, Tapas K., Chakrabarty, Ananda M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC387323/
https://ncbi.nlm.nih.gov/pubmed/15044691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400899101
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