Kappa Opioid Receptor Activation Decreases Inhibitory Transmission and Antagonizes Alcohol Effects in Rat Central Amygdala

Activation of the kappa opioid receptor (KOR) system mediates negative emotional states and considerable evidence suggests that KOR and their natural ligand, dynorphin, are involved in ethanol dependence and reward. The central amygdala (CeA) plays a major role in alcohol dependence and reinforcemen...

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Main Authors: Gilpin, Nicholas W., Roberto, Marisa, Koob, George F., Schweitzer, Paul
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873141/
https://ncbi.nlm.nih.gov/pubmed/24157490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.10.005
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