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Kappa Opioid Receptor Activation Decreases Inhibitory Transmission and Antagonizes Alcohol Effects in Rat Central Amygdala

Activation of the kappa opioid receptor (KOR) system mediates negative emotional states and considerable evidence suggests that KOR and their natural ligand, dynorphin, are involved in ethanol dependence and reward. The central amygdala (CeA) plays a major role in alcohol dependence and reinforcemen...

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Main Authors: Gilpin, Nicholas W., Roberto, Marisa, Koob, George F., Schweitzer, Paul
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873141/
https://ncbi.nlm.nih.gov/pubmed/24157490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.10.005
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