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Quantification of 8-OxodGuo Lesions in Double-Stranded DNA Using a Photoelectrochemical DNA Sensor

[Image: see text] Exposure of DNA to oxidative stress conditions results in the generation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo). 8-OxodGuo is genotoxic if left unrepaired. We quantified 8-oxodGuo lesions in double-stranded DNA films by using a photoelectrochemical DNA sensor in conjunc...

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Autors principals: Zhang, Bintian, Guo, Liang-Hong, Greenberg, Marc M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872968/
https://ncbi.nlm.nih.gov/pubmed/22746252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300866u
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