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Quantification of 8-OxodGuo Lesions in Double-Stranded DNA Using a Photoelectrochemical DNA Sensor
[Image: see text] Exposure of DNA to oxidative stress conditions results in the generation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo). 8-OxodGuo is genotoxic if left unrepaired. We quantified 8-oxodGuo lesions in double-stranded DNA films by using a photoelectrochemical DNA sensor in conjunc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872968/ https://ncbi.nlm.nih.gov/pubmed/22746252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300866u |
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