Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

Pulmonary emphysema, a significant global health problem, is characterized by a loss of alveolar structures. Because VEGF is a trophic factor required for the survival of endothelial cells and is abundantly expressed in the lung, we hypothesized that chronic blockade of VEGF receptors could induce a...

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Bibliographic Details
Main Authors: Kasahara, Yasunori, Tuder, Rubin M., Taraseviciene-Stewart, Laimute, Le Cras, Timothy D., Abman, Steven, Hirth, Peter K., Waltenberger, Johannes, Voelkel, Norbert F.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387249/
https://ncbi.nlm.nih.gov/pubmed/11104784
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