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Dual Phosphorylation of Cdk1 Coordinates Cell Proliferation with Key Developmental Processes in Drosophila

Eukaryotic organisms use conserved checkpoint mechanisms that regulate Cdk1 by inhibitory phosphorylation to prevent mitosis from interfering with DNA replication or repair. In metazoans, this checkpoint mechanism is also used for coordinating mitosis with dynamic developmental processes. Inhibitory...

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Hlavní autoři: Ayeni, Joseph O., Varadarajan, Ramya, Mukherjee, Oindrila, Stuart, David T., Sprenger, Frank, Srayko, Martin, Campbell, Shelagh D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872185/
https://ncbi.nlm.nih.gov/pubmed/24214341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.156281
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