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Drosophila Myt1 Is the Major Cdk1 Inhibitory Kinase for Wing Imaginal Disc Development

Mitosis is triggered by activation of Cdk1, a cyclin-dependent kinase. Conserved checkpoint mechanisms normally inhibit Cdk1 by inhibitory phosphorylation during interphase, ensuring that DNA replication and repair is completed before cells begin mitosis. In metazoans, this regulatory mechanism is a...

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Detalhes bibliográficos
Main Authors: Jin, Zhigang, Homola, Ellen, Tiong, Stanley, Campbell, Shelagh D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600946/
https://ncbi.nlm.nih.gov/pubmed/18940789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.093195
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