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How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis

Thyroid stimulating hormone (TSH) activates two major G-protein arms, Gsα and Gq leading to initiation of down-stream signaling cascades for survival, proliferation and production of thyroid hormones. Antibodies to the TSH receptor (TSHR-Abs), found in patients with Graves’ disease, may have stimula...

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Bibliografski detalji
Glavni autori: Morshed, Syed A., Ma, Risheng, Latif, Rauf, Davies, Terry F.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872079/
https://ncbi.nlm.nih.gov/pubmed/23958398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.07.009
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