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How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis
Thyroid stimulating hormone (TSH) activates two major G-protein arms, Gsα and Gq leading to initiation of down-stream signaling cascades for survival, proliferation and production of thyroid hormones. Antibodies to the TSH receptor (TSHR-Abs), found in patients with Graves’ disease, may have stimula...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872079/ https://ncbi.nlm.nih.gov/pubmed/23958398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.07.009 |
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