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Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against Influenza A virus

Inducing memory CD8(+) T-cells specific for conserved antigens from Influenza A virus (IAV) is a potential strategy for broadly protective vaccines. Here we show that memory CD8 T-cells in the airways played an important role in early control of IAV. Expression of chemokine receptor CXCR3 was critic...

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Detalhes bibliográficos
Main Authors: Slütter, Bram, Pewe, Lecia L., Kaech, Susan M., Harty, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872058/
https://ncbi.nlm.nih.gov/pubmed/24238342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.09.013
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