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Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria

H(2)O(2) production by skeletal muscle mitochondria oxidizing palmitoylcarnitine was examined under two conditions: the absence of respiratory chain inhibitors and the presence of myxothiazol to inhibit complex III. Without inhibitors, respiration and H(2)O(2) production were low unless carnitine or...

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Main Authors: Perevoshchikova, Irina V., Quinlan, Casey L., Orr, Adam L., Gerencser, Akos A., Brand, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871980/
https://ncbi.nlm.nih.gov/pubmed/23583329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.006
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