Strategies for Molecularly Enhanced Chemotherapy to Achieve Synthetic Lethality in Endometrial Tumors with Mutant p53

Serous uterine endometrial carcinomas are aggressive type II cancers with poor outcomes for which new treatment strategies are urgently needed, in particular, strategies that augment sensitivity to established chemotherapy regimens. The tumor suppressor gene TP53 is dysregulated in more than 90% of...

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Detalhes bibliográficos
Main Authors: Meng, Xiangbing, Dizon, Don S., Yang, Shujie, Wang, Xinjun, Zhu, Danlin, Thiel, Kristina W., Leslie, Kimberly K.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871910/
https://ncbi.nlm.nih.gov/pubmed/24381593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/828165
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