Mapping rat megalin: the second cluster of ligand binding repeats contains a 46-amino acid pathogenic epitope involved in the formation of immune deposits in Heymann nephritis.

Megalin (gp330), an epithelial endocytic receptor, is a major target antigen of Heymann nephritis (HN), an autoimmune disease in rats. To elucidate the mechanisms of HN, we have mapped a pathogenic epitope in megalin that binds anti-megalin antibodies. We focused our attention on four clusters of cy...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Saito, A, Yamazaki, H, Rader, K, Nakatani, A, Ullrich, R, Kerjaschki, D, Orlando, R A, Farquhar, M G
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC38719/
https://ncbi.nlm.nih.gov/pubmed/8710917
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