Hodgkin-Reed-Sternberg Cells in Classical Hodgkin Lymphoma Show Alterations of Genes Encoding the NADPH Oxidase Complex and Impaired Reactive Oxygen Species Synthesis Capacity

The membrane bound NADPH oxidase involved in the synthesis of reactive oxygen species (ROS) is a multi-protein enzyme encoded by CYBA, CYBB, NCF1, NCF2 and NCF4 genes. Growing evidence suggests a role of ROS in the modulation of signaling pathways of non-phagocytic cells, including differentiation a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Giefing, Maciej, Winoto-Morbach, Supandi, Sosna, Justyna, Döring, Claudia, Klapper, Wolfram, Küppers, Ralf, Böttcher, Sebastian, Adam, Dieter, Siebert, Reiner, Schütze, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871653/
https://ncbi.nlm.nih.gov/pubmed/24376854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084928
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi