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Basic Mechanics of DNA Methylation and the Unique Landscape of the DNA Methylome in Metal-Induced Carcinogenesis

DNA methylation plays an intricate role in the regulation of gene expression and events that compromise the integrity of the methylome may potentially contribute to disease development. DNA methylation is a reversible and regulatory modification that elicits a cascade of events leading to chromatin...

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Detalhes bibliográficos
Main Authors: Brocato, Jason, Costa, Max
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871623/
https://ncbi.nlm.nih.gov/pubmed/23844698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10408444.2013.794769
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