Effects of Inhibition of Serine Palmitoyltransferase (SPT) and Sphingosine Kinase 1 (SphK1) on Palmitate Induced Insulin Resistance in L6 Myotubes

BACKGROUND: The objective of this study was to examine the effects of short (2 h) and prolonged (18 h) inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate (PA) induced insulin resistance in L6 myotubes. METHODS: L6 myotubes were treated simultaneously with e...

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Bibliografiska uppgifter
Huvudupphovsmän: Mikłosz, Agnieszka, Łukaszuk, Bartłomiej, Baranowski, Marcin, Górski, Jan, Chabowski, Adrian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871603/
https://ncbi.nlm.nih.gov/pubmed/24376889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085547
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