Interleukin-1β and Interleukin-1 Receptor Antagonist Appear in Grey Matter Additionally to White Matter Lesions during Experimental Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) has been mainly attributed to white matter (WM) pathology. However, recent evidence indicated the presence of grey matter (GM) lesions. One of the principal mediators of inflammatory processes is interleukin-1β (IL-1β), which is known to play a role in MS pathogen...

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Detalhes bibliográficos
Main Authors: Prins, Marloes, Eriksson, Charlotta, Wierinckx, Anne, Bol, John G. J. M., Binnekade, Rob, Tilders, Fred J. H., Van Dam, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871572/
https://ncbi.nlm.nih.gov/pubmed/24376764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083835
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