Interleukin-1β and Interleukin-1 Receptor Antagonist Appear in Grey Matter Additionally to White Matter Lesions during Experimental Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) has been mainly attributed to white matter (WM) pathology. However, recent evidence indicated the presence of grey matter (GM) lesions. One of the principal mediators of inflammatory processes is interleukin-1β (IL-1β), which is known to play a role in MS pathogen...

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Autors principals: Prins, Marloes, Eriksson, Charlotta, Wierinckx, Anne, Bol, John G. J. M., Binnekade, Rob, Tilders, Fred J. H., Van Dam, Anne-Marie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871572/
https://ncbi.nlm.nih.gov/pubmed/24376764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083835
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