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Maintained expression of genes associated with metabolism in the ventromedial hypothalamic nucleus despite development of leptin resistance during pregnancy in the rat

Hyperphagia and weight gain to acquire energy stores for development and growth of the fetus and to prepare for the demands of lactation are important adaptations to support a healthy pregnancy. As a consequence, hypothalamic leptin resistance develops to enable maintenance of a positive energy stat...

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Détails bibliographiques
Auteurs principaux: Phillipps, Hollian R, Ladyman, Sharon R, Grattan, David R
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871476/
https://ncbi.nlm.nih.gov/pubmed/24400163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.162
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