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Maintained expression of genes associated with metabolism in the ventromedial hypothalamic nucleus despite development of leptin resistance during pregnancy in the rat

Hyperphagia and weight gain to acquire energy stores for development and growth of the fetus and to prepare for the demands of lactation are important adaptations to support a healthy pregnancy. As a consequence, hypothalamic leptin resistance develops to enable maintenance of a positive energy stat...

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Autors principals: Phillipps, Hollian R, Ladyman, Sharon R, Grattan, David R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871476/
https://ncbi.nlm.nih.gov/pubmed/24400163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.162
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