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Functional expression of a human Na+/H+ antiporter gene transfected into antiporter-deficient mouse L cells.

To clone the gene for the human Na+/H+ antiporter, we first constructed a stable mouse LTK- cell line (LAP1) lacking Na+/H+ antiport activity. Second, we devised a selective technique based on acid killing that specifically sorts out cells expressing low levels of Na+/H+ antiport activity from a pop...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Franchi, A, Perucca-Lostanlen, D, Pouyssegur, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025840/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9388
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