Functional expression of a human Na+/H+ antiporter gene transfected into antiporter-deficient mouse L cells.
To clone the gene for the human Na+/H+ antiporter, we first constructed a stable mouse LTK- cell line (LAP1) lacking Na+/H+ antiport activity. Second, we devised a selective technique based on acid killing that specifically sorts out cells expressing low levels of Na+/H+ antiport activity from a pop...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1986
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9388 |
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