Improved free-energy parameters for predictions of RNA duplex stability.

Thermodynamic parameters for prediction of RNA duplex stability are reported. One parameter for duplex initiation and 10 parameters for helix propagation are derived from enthalpy and free-energy changes for helix formation by 45 RNA oligonucleotide duplexes. The oligomer sequences were chosen to ma...

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Hauptverfasser: Freier, S M, Kierzek, R, Jaeger, J A, Sugimoto, N, Caruthers, M H, Neilson, T, Turner, D H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387140/
https://ncbi.nlm.nih.gov/pubmed/2432595
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