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The proteolytic fragments generated by vertebrate proteasomes: structural relationships to major histocompatibility complex class I binding peptides.

Proteasomes are involved in the proteolytic generation of major histocompatibility complex (MHC) class I epitopes but their exact role has not been elucidated. We used highly purified murine 20S proteasomes for digestion of synthetic 22-mer and 41/44-mer ovalbumin partial sequences encompassing eith...

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Main Authors: Niedermann, G, King, G, Butz, S, Birsner, U, Grimm, R, Shabanowitz, J, Hunt, D F, Eichmann, K
Format: Artigo
Jezik:Inglês
Izdano: 1996
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC38714/
https://ncbi.nlm.nih.gov/pubmed/8710912
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