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Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.

A gene, PDE2, has been cloned from the yeast Saccharomyces cerevisiae that, when present in high copy, reverses the phenotypic effects of RAS2Val19, a mutant form of the RAS2 gene that renders yeast cells sensitive to heat shock and starvation. It has previously been shown that the RAS proteins are...

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Bibliographic Details
Main Authors: Sass, P, Field, J, Nikawa, J, Toda, T, Wigler, M
Format: Artigo
Language:Inglês
Published: 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387126/
https://ncbi.nlm.nih.gov/pubmed/3025832
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