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Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.

A gene, PDE2, has been cloned from the yeast Saccharomyces cerevisiae that, when present in high copy, reverses the phenotypic effects of RAS2Val19, a mutant form of the RAS2 gene that renders yeast cells sensitive to heat shock and starvation. It has previously been shown that the RAS proteins are...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sass, P, Field, J, Nikawa, J, Toda, T, Wigler, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9303
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