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Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase.

A rat brain cDNA library has been constructed in a Saccharomyces cerevisiae expression vector and used to isolate genes that can function in yeast to suppress the phenotypic effects of RAS2val19, a mutant form of the RAS2 gene analogous to an oncogenic mutant of the human HRAS gene. One cDNA, DPD, w...

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Dettagli Bibliografici
Autori principali: Colicelli, J, Birchmeier, C, Michaeli, T, O'Neill, K, Riggs, M, Wigler, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC287185/
https://ncbi.nlm.nih.gov/pubmed/2542941
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