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Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase.

A rat brain cDNA library has been constructed in a Saccharomyces cerevisiae expression vector and used to isolate genes that can function in yeast to suppress the phenotypic effects of RAS2val19, a mutant form of the RAS2 gene analogous to an oncogenic mutant of the human HRAS gene. One cDNA, DPD, w...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Colicelli, J, Birchmeier, C, Michaeli, T, O'Neill, K, Riggs, M, Wigler, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287185/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3599
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