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The permeability of gamma-aminobutyric acid-gated chloride channels is described by the binding of a "cage" convulsant, t-butylbicyclophosphoro[35S]thionate.

The "cage" convulsant t-butylbicyclophosphoro[35S]thionate ([35S]TBPS) binds with high affinity to sites at or near a gamma-aminobutyric acid (GABA)-gated chloride channel according to current hypothesis. We now report that the potencies of a series of anions in enhancing [35S]TBPS binding...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Havoundjian, H, Paul, S M, Skolnick, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2431413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.23.9241
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