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Chemical Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with Substituted Amino Moiety

Novel pleuromutilin derivatives designed based on the structure of valnemulin were synthesized and evaluated for their in vitro antibacterial activities. These pleuromutilin derivatives with substituted amino moiety exhibited excellent activities against methicillin-resistant Staphylococcus aureus,...

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Detalhes bibliográficos
Main Authors: Shang, Ruofeng, Wang, Shengyu, Xu, Ximing, Yi, Yunpeng, Guo, Wenzhu, YuLiu, Liang, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871055/
https://ncbi.nlm.nih.gov/pubmed/24376551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082595
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