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Synthesis and Biological Evaluation of New Pleuromutilin Derivatives as Antibacterial Agents

Several pleuromutilin derivatives possessing thiadiazole moieties were synthesized via acylation reactions under mild conditions. The in vitro antibacterial activities of the derivatives against methicillin-resistant S. aureus, methicillin-resistant S. epidermidis, S. aureus, S. epidermidis, E. coli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Shang, Ruo-Feng, Wang, Guan-Hua, Xu, Xi-Ming, Liu, Si-Jie, Zhang, Chao, Yi, Yun-Peng, Liang, Jian-Ping, Liu, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271455/
https://ncbi.nlm.nih.gov/pubmed/25415471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191119050
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