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Influence of 8-Oxoguanosine on the Fine Structure of DNA Studied with Biasing-Potential Replica Exchange Simulations

Chemical modification or radiation can cause DNA damage, which plays a crucial role for mutagenesis of DNA, carcinogenesis, and aging. DNA damage can also alter the fine structure of DNA that may serve as a recognition signal for DNA repair enzymes. A new, advanced sampling replica-exchange method h...

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Autors principals: Kara, Mahmut, Zacharias, Martin
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870923/
https://ncbi.nlm.nih.gov/pubmed/23473492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.032
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