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Folding of a DNA Hairpin Loop Structure in Explicit Solvent Using Replica-Exchange Molecular Dynamics Simulations

Hairpin loop structures are common motifs in folded nucleic acids. The 5′-GCGCAGC sequence in DNA forms a characteristic and stable trinucleotide hairpin loop flanked by a two basepair stem helix. To better understand the structure formation of this hairpin loop motif in atomic detail, we employed r...

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Detaylı Bibliyografya
Asıl Yazarlar: Kannan, Srinivasaraghavan, Zacharias, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025651/
https://ncbi.nlm.nih.gov/pubmed/17660316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108019
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