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Folding of a DNA Hairpin Loop Structure in Explicit Solvent Using Replica-Exchange Molecular Dynamics Simulations
Hairpin loop structures are common motifs in folded nucleic acids. The 5′-GCGCAGC sequence in DNA forms a characteristic and stable trinucleotide hairpin loop flanked by a two basepair stem helix. To better understand the structure formation of this hairpin loop motif in atomic detail, we employed r...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Biophysical Society
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2025651/ https://ncbi.nlm.nih.gov/pubmed/17660316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108019 |
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