Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen.

The neu oncogene encodes a 185-kDa transmembrane glycoprotein tumor antigen, termed p185. We have recently described a monoclonal antibody reactive with a cell surface domain of the p185 molecule. In vivo treatment with this anti-p185 monoclonal antibody was able to significantly inhibit the tumorig...

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Bibliographic Details
Main Authors: Drebin, J A, Link, V C, Weinberg, R A, Greene, M I
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387088/
https://ncbi.nlm.nih.gov/pubmed/3466178
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