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The Role of the Dysfunctional Akt-Related Pathway in Cancer: Establishment and Maintenance of a Malignant Cell Phenotype, Resistance to Therapy, and Future Strategies for Drug Development

Akt serine/threonine kinases, or PKB, are key players in the regulation of a wide variety of cellular activities, such as growth, proliferation, protection from apoptotic injuries, control of DNA damage responses and genome stability, metabolism, migration, and angiogenesis. The Akt-related pathway...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Romano, Gaetano
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Hindawi Publishing Corporation 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870877/
https://ncbi.nlm.nih.gov/pubmed/24381788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/317186
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