Lentiviral Delivery of a Vesicular Glutamate Transporter 1 (VGLUT1)-Targeting Short Hairpin RNA Vector Into the Mouse Hippocampus Impairs Cognition

Glutamate is the principle excitatory neurotransmitter in the mammalian brain, and dysregulation of glutamatergic neurotransmission is implicated in the pathophysiology of several psychiatric and neurological diseases. This study utilized novel lentiviral short hairpin RNA (shRNA) vectors to target...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: King, Madeleine V, Kurian, Nisha, Qin, Si, Papadopoulou, Nektaria, Westerink, Ben HC, Cremers, Thomas I, Epping-Jordan, Mark P, Le Poul, Emmanuel, Ray, David E, Fone, Kevin CF, Kendall, David A, Marsden, Charles A, Sharp, Tyson V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870793/
https://ncbi.nlm.nih.gov/pubmed/24037344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.220
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