Inositol-Related Gene Knockouts Mimic Lithium's Effect on Mitochondrial Function

The inositol-depletion hypothesis proposes that lithium attenuates phosphatidylinositol signaling. Knockout (KO) mice of two genes (IMPA1 or Slc5a3), each encoding for a protein related to inositol metabolism, were studied in comparison with lithium-treated mice. Since we previously demonstrated tha...

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Hlavní autoři: Toker, Lilach, Bersudsky, Yuly, Plaschkes, Inbar, Chalifa-Caspi, Vered, Berry, Gerard T, Buccafusca, Roberto, Moechars, Dieder, Belmaker, R H, Agam, Galila
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870788/
https://ncbi.nlm.nih.gov/pubmed/23924600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.194
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