Varenicline and Cytisine Diminish the Dysphoric-Like State Associated with Spontaneous Nicotine Withdrawal in Rats

Tobacco addiction is characterized by a negative mood state upon smoking cessation and relapse after periods of abstinence. Clinical studies indicate that negative mood states lead to craving and relapse. The partial α4/α6/β2* nicotinic acetylcholine receptor (nAChR) agonists varenicline and cytisin...

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Autori principali: Igari, Moe, Alexander, Jon C, Ji, Yue, Qi, Xiaoli, Papke, Roger L, Bruijnzeel, Adrie W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870769/
https://ncbi.nlm.nih.gov/pubmed/23966067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.216
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