Autosis is a Na(+),K(+)-ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia

A long-standing controversy is whether autophagy is a bona fide cause of mammalian cell death. We used a cell-penetrating autophagy-inducing peptide, Tat-Beclin 1, derived from the autophagy protein Beclin 1, to investigate whether high levels of autophagy result in cell death by autophagy. Here we...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Shoji-Kawata, Sanae, Sumpter, Rhea M., Wei, Yongjie, Ginet, Vanessa, Zhang, Liying, Posner, Bruce, Tran, Khoa A., Green, Douglas R., Xavier, Ramnik J., Shaw, Stanley Y., Clarke, Peter G. H., Puyal, Julien, Levine, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870705/
https://ncbi.nlm.nih.gov/pubmed/24277826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319661110
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