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Quantitative exploration of the molecular origin of the activation of GTPase

GTPases play a major role in cellular processes, and gaining quantitative understanding of their activation demands reliable free energy surfaces of the relevant mechanistic paths in solution, as well as the interpolation of this information to GTPases. Recently, we generated ab initio quantum mecha...

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Bibliographische Detailangaben
Hauptverfasser: B, Ram Prasad, Plotnikov, Nikolay V., Lameira, Jeronimo, Warshel, Arieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870692/
https://ncbi.nlm.nih.gov/pubmed/24282301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319854110
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